CS / EN
Institute of Molecular Genetics of the Czech Academy of Sciences, Prague
Patent: CZ 308596
Dvořák, M, Dvořáková M, Karafiát V, Štursa J, Werner L. Derivatives of phospholipids and their use as pharmaceuticals
Patent: US 10350176
Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition consisting of diphenyleneiodonium for treating diseases caused by the parasites belonging to the family trypanosomatidae
Patent: CZ 307437
Kotora M, Prchalová E, Adamski J, Moller G, Stěpánek O, Bartůněk P, Sedlák D, Hajduch M, Dzubak P. 15β-substituted estrone derivatives as selective inhibitors of 17β-hydroxysteoid dehydrogenases
Patent: CZ 307916
Stoniš J, Mikeš I, Doležalová A, Králová J, Jakubek M, Martásek P, Král V. Orodispersible tablet with bioavailable curcumin and its use.
Patent: CZ 307772
Havlík M, Bříza T, Kaplánek R, Králová J, Martásek P, Král V. The coumarin derivative of the Tröger base with cyanine substitution and its use
Patent: CZ 307237
Staňková P, Štěpán J, Demele J, Slováček Z, Králová J, Martásek P, Král V. A supramolecular complex of an oxycellulose matrix with a taxol derivative with sequential release of the taxol derivative and its use.
Patent: CZ 307155
Staňková P, Štěpán J, Demele J, Slováček Z, Králová J, Martásek P, Král V.  A supramolecular complex of an oxycellulose matrix with an anthracycline cytostatic with sequential release of an anthracycline cytostatic and its use.
Patent: CZ 307235
Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A,Martásek P, Král V. A symmetric derivative of Tröger's base with tetramethine substitution and its use.
Patent: CZ 307234
Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A,Martásek P, Král V.  An asymmetric derivative of Tröger's base with tetramethinium substitution and its use.
Patent: EP 3054941
Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition comprising diphenyleneiodonium for treating diseases caused by the parasites belonging to the family Trypanosomatidae.
Patent: CZ 306849
Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A, Martásek P,  Král V. An asymmetric derivative of Tröger's base with dimethinium substitution and its use.
Patent: EP 2927230
Kral V, Havlik M, Kaplanek R, Dolensky B, Ruml T, Rimpelova S, Martasek P, Briza T, Kejik Z, Rak J, Kralova J. Pentamethinium salts with an expanded quinoxaline unit and its use in anticancer therapy.
Patent: CZ 306011
Bartůněk P, Kořínek V, Pombinho A, Tůmová L. Monesin-containing pharmaceutical composition for treating diseases associated with deregulated Wnt pathway.
Patent: CZ 305247
Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition containing diphenyleneiodonium for treating diseases caused by parasites of Trypanosomatidae species
Patent: EP 2527351
Rejman D, Pohl R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use
Patent: CZ 303569
Rejman D, Pohl  R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use
Patent: US 8334280
Patent: EP 2274316
Novák P, Sedlák D, Bartůněk P, Kotora M. Ligands of estrogen receptors α and β, method of their preparation and pharmaceuticals comprising them
Patent: CZ 300376
Novák P, Sedlák D, Bartůněk P, Kotora M. Estrogen receptors alpha and beta ligands, method for their preparation and pharmaceutical agents comprising thereof
Patent: US 11020411 B2
Patent: AU 2016324495 B2
Tjarks W, Bartunek P, Sedlak D, Carborane compounds and methods of use thereof.
Institute of Molecular and Translational Medicine, Olomouc
Patent: US 10730905
Patent: JP 6685475
Patent: EP 3494122
Patent: CZ 307334
Hocek M, Tokarenko A, Smoleń S, Džubák P, Hajdúch M. Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use.
Patent: CZ 306554
Kaplánek R, Bříza T, Havlík M, Rak J, Kejík Z, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Benzoisothiazole-1,1-dioxide-3-hydrazones and their use in anticancer therapy.
Patent: US 9586986
Hocek M, Nauš P, Caletková O, Džubák P, Hajdúch M. Substituted 7-dezapurin ribonucleosides.
Patent: CZ 305626
Kaplánek R, Bříza T, Havlík M, Rak J, Kejík Z, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Dioxocyclobutenyl hydrazones and their anticancer activity.
Patent: CZ 305625
Kaplánek R, Jakubek M, Havlík M, Rak J, Bříza T, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Caffeine-8-hydrazones as novel cytostatics for the treatment of oncologic diseases.
Patent: CZ 305607
Rak J, Kaplánek R, Štulcová T, Drašar P, Havlík M, Bříza T, Džubák P, Hajdúch M, Konečný P,  Štěpánková J, Králová J, Král V. Cholyl hydrazones and their use in the treatment of tumor and leukemia diseases.
Patent: CZ 305683
Havlík M, Kaplánek R, Dolenský B, Rak J, Bříza T, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Asymmetric Troger bases with hydrazone group and their use in the treatment of oncologic diseases.
Patent: US 8299092
Krejčí P, Hradil P, Hlaváč J, Hajdúch M. Derivates of 2-phenyl-3-hydroxyquinoline-4(1h)-one and methods of their preparation and utilization.
Patent: EP 2349283
Šarek J, Spáčilová P, Hajdúch M. Triperpenoid 2-deoxy glycosides and use thereof as medicaments.
Patent: US 8653056 B2
Šarek J, Hajdúch M, Svoboda M, Nováková K, Spáčilová P, Kubelka T, Biedermann D. Method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, a soluble formulation of a pentacyclic or tetracyclic terpenoid and a pharmaceutical composition containing this soluble formulation.
Patent: US 8093413 B2
Šarek J, Svoboda M, Hajdúch M. Method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin.
Patent: US 7 858 606 B2
Hajdúch M, Šarek J. Triterpenoid derivatives.
Patent: EP 1 458 742 B1
Fischer P, Šarek J, Blaney P, Collier P, Ferguson J, Hull JD, Hajdúch M. Solvates of 3.Beta, 28-diacetoxy-18-oxo-19, 20, 21, 29, 30-pentanorlupan-22-oic acid, processes for their preparation and pharmaceutical compositions thereof.
Patent: CZ 305 683
Rak J, Kaplánek R, Štulcová T, Drašar P, Havlík M, Bříza T, Džubák P, Hajdúch M, Konečný P, Stěpánková J, Králová J, Král V. Asymetric troger bases with hydrazone group and their use in the treatment of oncologic diseases
Institute of Chemistry, Faculty of Science, Masaryk University, Brno
Patent: EP 2940022
Paruch K, Petrůjová M. Furopyridines as inhibitors of protein kinases.
Patent: EP 3556756
Paruch K, Carbain B, Havel S, Všiansky V, Nikulenkov F, Krejčí L. Substituted propanamides as inhibitors of nucleases.
Patent: CZ 305472
Paruch K, Petrůjová M. Substituted furo[3,2-b]pyridines intended for use as medicaments.
Patent: US 9902733
Patent: JP 6386585
Paruch K, Petrůjová M, Němec V. Furopyridines as inhibitors of protein kinases.
Patent: US 9969741
Patent: JP 6313906
Patent: EP 2957562
Damborsky J, Nikulenkov F, Sisáková A, Havel Š, Krejčí L, Carbain B, Brezovsky J, Daniel L, Paruch K. Pyrazolotriazines as inhibitors of nucleases.
Patent: AU 2019246220 B2
Bryja V, Janovská P, Gregorová M, Němec V, Khirsariya P, Paruch K. 4-(1H-imidazol-5-yl)-1H-pyrrolo[2,3-b]pyridines for use in the treatment of leukaemias, lymphomas and solid tumors. AU 2019246220 B2
Patent: US 11584742
Paruch K, Carbain B, Havel Š, Damborský J, Brezovský J, Daniel L, Sisáková A, Nikulenkov F, Krejčí L. Substituted aminothiazoles as inhibitors of nucleases.
Patent: AU 2019256672
Paruch K, Carbain B, Havel Š, Všianský V, Nikulenkov F, Krejčí L. Substituted propanamides as inhibitors of nucleases.