Introduction

CZ-OPENSCREEN: National infrastructure for chemical biology is the state-of-the-art infrastructure for basic and applied research in the fields of chemical biology and genetics and provides Open Access to users. The mission of CZ-OPENSREEN is to identify new molecular probes/tools for research and proof-of-concept compounds for the development of new potential therapeutics.  Moreover, our infrastructure serves as the National node of the pan-European ESFRI infrastructure EU-OPENSCREEN, which integrates high-capacity screening platforms through Europe and provides access to the European Chemical Biology Database (ECBD). CZ-OPENSCREEN offers services not only to Czech but to international users as well.

CZ-OPENSCREEN represents a multipurpose platform and covers all areas of biology (from simple biomedical studies of proteins, via cellular testing to advanced tests of the whole organisms. conducts high-throughput screening (HTS) and High -Content Screening (HCS) the preparation of compounds (automated systems for storage and formatting compounds) and the optimization of newly identified biologically active compounds (organic and medicinal chemistry). We offer data analysis, data storage and potentially make the data available to the scientific community (cheminformatics, bioinformatics, complex data mining).