ChemGenDB is a web application for handling of chemical-biological data. It is capable of storing information about chemical samples, their properties and structures, substructure and similarity searching, organizing samples into chemical plates, handling of 1D and 2D barcodes for samples and plates, plate reformat (clone, serial dilution, Z-reformat), creating assay plates and arranging them into biological experiments, automatic import of result data to experiments, experiment visualisation and analysis (dose-response curves computation, fragment analysis, cluster analysis, etc.).