CS / EN
CZ-OPENSCREEN is managed by the Management Board that is advised by the International advisory board and several other committees. 
Organization scheme
Management Board
Steering committee
Petr Dráber, Ph.D., DSc. (Director, Institute of Molecular Genetics, Prague)
Prof. Mgr. Tomáš Kašparovský, Ph.D. (Dean, Faculty of Science, Masaryk University, Brno)
Prof. MUDr. Josef Zadražil, CSc. (Dean, Faculty of Medicine and Dentistry, Palacký University, Olomouc)
International Advisory Scientific Board
Dr. Phil Gribbon ( Fraunhofer Institute for Molecular Biology and Applied Ecology IME , Hamburg, Germany), chairman
Prof. Kjetil Tasken ( University of Oslo, Institute of Clinical Medicine , Oslo, Norway)
Prof. Mikael Elofsson ( Umeå University , Umeå, Sweden)
Dr. John Overington ( Medicines Discovery Catapult , Cheshire, United Kingdom)
Dr. Jordi Quintana ( Universitat Pompeu Fabra , Barcelona, Spain)
Open Access Committees
Biology
Cyril Bařinka, PhD. ( Institute of Biotechnology ASCR, v.v.i. , Prague)
Martin Pospíšek, PhD. ( Department of Genetics and Microbiology , Faculty of Science, Charles University, Prague)
Medicinal Chemistry
Assoc. Prof. Daniel Růžek, PhD. ( Institute of Parasitology Biology Centre of the Czech Academy of Sciences , České Budějovice)
Cheminformatics
RNDr. Marián Rucki, PhD. ( The National Institute of Public Health , Prague)
Management and administration
Administrative team
Assay development and High-throughput screening
Laboratory automation and Compound management
Cheminformatics and software development
We are looking for a highly motivated colleague for the identification of bioactive compounds and potential drugs. The role includes developing enzymatic assays for profiling chemical compound libraries, designing and conducting high-throughput screening experiments, operating a mass spectrometer coupled with acoustic ejection and liquid chromatography (UHPLC, I-Class, Waters), and maintaining and calibrating the Sciex Triple Quad 6500 mass spectrometer. Advanced data analysis and knowledge extraction from data will also be key responsibilities. Join our team to contribute to cutting-edge research in chemical biology.
current
past
Modernization of the National Infrastructure for Chemical Biology 2024
Identification code
CZ.02.01.01/00/23_015/0008203
State funding provider
Ministry of Education, Youth and Sports
Programme
Programme Johannes Amos Comenius
Research years
1. 1. 2024 – 31. 12. 2026
Description
The main mission of the National infrastructure of chemical biology (CZ-OPENSCREEN) is the screening of biological activities of compounds and the identification of tools, probes and methods to be used in the basic research of cellular processes, mechanisms of disease genesis and pathophysiological cellular pathway intervention. The main objective of the project is to modernise the CZ-OPENSCREEN infrastructure through the following key activities KA1 Project management, KA2 Modernisation of IMG laboratories, KA3 Modernisation of UPOL laboratories, KA4 Modernisation of MU laboratories, KA5 Modernisation of UCT laboratories and KA6 Building reconstruction at IMG. The investment in new laboratories and key equipment will clearly contribute to a further increase in the international quality of research and its results within the infrastructure, while increasing competitiveness not only at the level of Czech science, but also of the Czech Republic itself.
National Infrastructure for Chemical Biology
Identification code
LM2023052
State funding provider
Ministry of Education, Youth and Sports
Programme
Large RDI infrastructures projects
Research years
1.1. 2023 - 31.12. 2026
Description
The mission of the project “National Infrastructure of Chemical Biology” is to support a research center conducting basic and applied research in the field of chemical biology and genetics and to provide open access to its users. CZ-OPENSCREEN Infrastructure is a national node of the EU OPENSCREEN ERIC, which allows access to the international research platform and the European compound library. The main objectives of the CZ-OPENSCREEN research infrastructure are the identification of new molecular probes and tools for further research and validation of compounds suitable for the development of new potential therapeutics. Chemical biology represents a new interdisciplinary scientific field linking traditional research disciplines (cell biology, molecular and structural biology, biochemistry, organic chemistry and chem/bioinformatics), thereby providing the desired support to deepen the knowledge to date.