Patents

INSTITUTE OF MOLECULAR GENETICS ASCR, v. v. i., Prague

Patent: CZ 307437

Kotora M, Prchalova E, Adamski J, Moller G, Stepanek O, Bartunek P, Sedlak D, Hajduch M, Dzubak P. 15β-substituted estrone derivatives as selective inhibitors of 17β-hydroxysteoid dehydrogenases

Patent: EP3054941

Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition comprising diphenyleneiodonium for treating diseases caused by the parasites belonging to the family Trypanosomatidae

Patent: CZ 306011

Bartůněk P, Kořínek V, Pombinho A, Tůmová L. Monesin-containing pharmaceutical composition for treating diseases associated with deregulated Wnt pathway

Patent: CZ 305247

Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition containing diphenyleneiodonium for treating diseases caused by parasites of Trypanosomatidae species

Patent: EP 2527351

Rejman D, Pohl R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use

Patent: CZ 303569

Rejman D, Pohl  R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use

Patent: US 8334280

Novák P, Sedlák D, Bartůněk P, Kotora M. Ligands of estrogen receptors α and β, method of their preparation and pharmaceuticals comprising them

Patent: EP 2274316

Novák P, Sedlák D, Bartůněk P, Kotora M. Ligands of estrogen receptors α and β, method of their preparation and pharmaceuticals comprising them

Patent: CZ 300376

Novák P, Sedlák D, Bartůněk P, Kotora M. Estrogen receptors alpha and beta ligands, method for their preparation and pharmaceutical agents comprising thereof

 

INSTITUTE OF MOLECULAR AND TRANSLATIONAL MEDICINE, Olomouc

Patent: EP 2602330 A1

Kollareddy MR, Hajdúch M, Džubák P, Srovnal J, Hrabáková R, Kovářová H. Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance.

 

Patent: US 8299092 B2

Krejčí P, Hradil P, Hlaváč J, Hajdúch M. Derivates of 2-phenyl-3-hydroxyquinoline-4(1h)-one and methods of their preparation and utilization.

 

Patent: EP 2349283 A2

Šarek J, Spáčilová P, Hajdúch M. Triperpenoid 2-deoxy glycosides and use thereof as medicaments.

 

Patent: US 8653056 B2

Šarek J, Hajdúch M, Svoboda M, Nováková K, Spáčilová P, Kubelka T, Biedermann D. Method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, a soluble formulation of a pentacyclic or tetracyclic terpenoid and a pharmaceutical composition containing this soluble formulation.

 

Patent: US 8093413 B2

Šarek J, Svoboda M, Hajdúch M. Method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin.

 

Patent: US 7 858 606 B2

Hajdúch M, Šarek J. Triterpenoid derivatives.

 

Patent: EP 1 458 742 B1

Fischer P, Šarek J, Blaney P, Collier P, Ferguson J, Hull JD, Hajdúch M. Solvates of 3.Beta, 28-diacetoxy-18-oxo-19, 20, 21, 29, 30-pentanorlupan-22-oic acid, processes for their preparation and pharmaceutical compositions thereof.

 

Patent: CZ 305 683

Rak J, Kaplánek R, Štulcová T, Drašar P, Havlík M, Bříza T, Džubák P, Hajdúch M, Konečný P, Stěpánková J, Králová J, Král V. Asymetric troger bases with hydrazone group and their use in the treatment of oncologic diseases

 

INSTITUTE OF CHEMISTRY, FACULTY OF SCIENCE, MASARYK UNIVERSITY, Brno

Patent: CZ 305472

Paruch K, Petrůjová M. Substituted furo[3,2-b]pyridines intended for use as medicaments.

 

Patent: WO 2015/165428 A1

Paruch, K.; Petrůjová, M.; Němec, V. Furopyridines as inhibitors of protein kinases.

 

Patent: WO 2015/192817 A1

Damborsky J, Nikulenkov F, Sisáková A, Havel Š, Krejčí L, Carbain B, Brezovsky J, Daniel L, Paruch K. Pyrazolotriazines as inhibitors of nucleases.