Patents

INSTITUTE OF MOLECULAR GENETICS ASCR, v. v. i., Prague

Patent: CZ 308596

Dvořák, M, Dvořáková M, Karafiát V, Štursa J, Werner L. Derivatives of phospholipids and their use as pharmaceuticals

Patent: US 10350176

Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition consisting of diphenyleneiodonium for treating diseases caused by the parasites belonging to the family trypanosomatidae

Patent: CZ 307437

Kotora M, Prchalová E, Adamski J, Moller G, Stěpánek O, Bartůněk P, Sedlák D, Hajduch M, Dzubak P. 15β-substituted estrone derivatives as selective inhibitors of 17β-hydroxysteoid dehydrogenases

Patent: CZ 307916

Stoniš J, Mikeš I, Doležalová A, Králová J, Jakubek M, Martásek P, Král V. Orodispersible tablet with bioavailable curcumin and its use.

Patent: CZ 307772

Havlík M, Bříza T, Kaplánek R, Králová J, Martásek P, Král V. The coumarin derivative of the Tröger base with cyanine substitution and its use

Patent: CZ 307237

Staňková P, Štěpán J, Demele J, Slováček Z, Králová J, Martásek P, Král V. A supramolecular complex of an oxycellulose matrix with a taxol derivative with sequential release of the taxol derivative and its use.

Patent: CZ 307155

Staňková P, Štěpán J, Demele J, Slováček Z, Králová J, Martásek P, Král V.  A supramolecular complex of an oxycellulose matrix with an anthracycline cytostatic with sequential release of an anthracycline cytostatic and its use.

Patent: CZ 307235

Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A,Martásek P, Král V. A symmetric derivative of Tröger's base with tetramethine substitution and its use.

Patent: CZ 307234

Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A,Martásek P, Král V.  An asymmetric derivative of Tröger's base with tetramethinium substitution and its use.

Patent: EP 3054941

Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition comprising diphenyleneiodonium for treating diseases caused by the parasites belonging to the family Trypanosomatidae.

Patent: CZ 306849

Havlík M, Bříza T, Kejík Z, Dolenský B, Kaplánek R, Rak J, Králová J, Šedo A, Martásek P,  Král V. An asymmetric derivative of Tröger's base with dimethinium substitution and its use.

Patent: EP 2927230

Kral V, Havlik M, Kaplanek R, Dolensky B, Ruml T, Rimpelova S, Martasek P, Briza T, Kejik Z, Rak J, Kralova J. Pentamethinium salts with an expanded quinoxaline unit and its use in anticancer therapy.

Patent: CZ 306011

Bartůněk P, Kořínek V, Pombinho A, Tůmová L. Monesin-containing pharmaceutical composition for treating diseases associated with deregulated Wnt pathway.

Patent: CZ 305247

Grekov I, Pombinho A, Šíma M, Kobets T, Bartůněk P, Lipoldová M. Pharmaceutical composition containing diphenyleneiodonium for treating diseases caused by parasites of Trypanosomatidae species

Patent: EP 2527351

Rejman D, Pohl R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use

Patent: CZ 303569

Rejman D, Pohl  R, Bartůněk P, Pombinho AR, Krásný L, Látal T. Lipophosphonoxins, method of their preparation and use

Patent: US 8334280

Novák P, Sedlák D, Bartůněk P, Kotora M. Ligands of estrogen receptors α and β, method of their preparation and pharmaceuticals comprising them

Patent: EP 2274316

Novák P, Sedlák D, Bartůněk P, Kotora M. Ligands of estrogen receptors α and β, method of their preparation and pharmaceuticals comprising them

Patent: CZ 300376

Novák P, Sedlák D, Bartůněk P, Kotora M. Estrogen receptors alpha and beta ligands, method for their preparation and pharmaceutical agents comprising thereof

 

INSTITUTE OF MOLECULAR AND TRANSLATIONAL MEDICINE, Olomouc

Patent: US 10730905

Hocek M, Tokarenko A, Smolen S, Hajdúch M, Džubák P. Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use.

Patent: JP 6685475

Hocek M., Tokarenko A, Smoleń S, Džubák P, Hajdúch M. Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use.

Patent: EP 3494122

Hocek M, Tokarenko A, Smoleń S, Džubák P, Hajdúch M. Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use.

Patent: CZ 307334

Hocek M, Tokarenko A, Smoleń S, Džubák P, Hajdúch M. Substituted heteropentadieno-pyrrolopyrimidine ribonucleosides for therapeutic use.

Patent: CZ 306554

Kaplánek R, Bříza T, Havlík M, Rak J, Kejík Z, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Benzoisothiazole-1,1-dioxide-3-hydrazones and their use in anticancer therapy.

Patent: US 9586986

Hocek M, Nauš P, Caletková O, Džubák P, Hajdúch M. Substituted 7-dezapurin ribonucleosides.

Patent: CZ 305626

Kaplánek R, Bříza T, Havlík M, Rak J, Kejík Z, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Dioxocyclobutenyl hydrazones and their anticancer activity.

Patent: CZ 305625

Kaplánek R, Jakubek M, Havlík M, Rak J, Bříza T, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Caffeine-8-hydrazones as novel cytostatics for the treatment of oncologic diseases.

Patent: CZ 305607

Rak J, Kaplánek R, Štulcová T, Drašar P, Havlík M, Bříza T, Džubák P, Hajdúch M, Konečný P,  Štěpánková J, Králová J, Král V. Cholyl hydrazones and their use in the treatment of tumor and leukemia diseases.

Patent: CZ 305683

Havlík M, Kaplánek R, Dolenský B, Rak J, Bříza T, Džubák P, Hajdúch M, Konečný P, Štěpánková J, Králová J, Král V. Asymmetric Troger bases with hydrazone group and their use in the treatment of oncologic diseases.

Patent: US 8299092

Krejčí P, Hradil P, Hlaváč J, Hajdúch M. Derivates of 2-phenyl-3-hydroxyquinoline-4(1h)-one and methods of their preparation and utilization.

Patent: EP 2349283

Šarek J, Spáčilová P, Hajdúch M. Triperpenoid 2-deoxy glycosides and use thereof as medicaments.

Patent: US 8653056 B2

Šarek J, Hajdúch M, Svoboda M, Nováková K, Spáčilová P, Kubelka T, Biedermann D. Method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, a soluble formulation of a pentacyclic or tetracyclic terpenoid and a pharmaceutical composition containing this soluble formulation.

Patent: US 8093413 B2

Šarek J, Svoboda M, Hajdúch M. Method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin.

Patent: US 7 858 606 B2

Hajdúch M, Šarek J. Triterpenoid derivatives.

Patent: EP 1 458 742 B1

Fischer P, Šarek J, Blaney P, Collier P, Ferguson J, Hull JD, Hajdúch M. Solvates of 3.Beta, 28-diacetoxy-18-oxo-19, 20, 21, 29, 30-pentanorlupan-22-oic acid, processes for their preparation and pharmaceutical compositions thereof.

Patent: CZ 305 683

Rak J, Kaplánek R, Štulcová T, Drašar P, Havlík M, Bříza T, Džubák P, Hajdúch M, Konečný P, Stěpánková J, Králová J, Král V. Asymetric troger bases with hydrazone group and their use in the treatment of oncologic diseases

 

INSTITUTE OF CHEMISTRY, FACULTY OF SCIENCE, MASARYK UNIVERSITY, Brno

Patent: EP 2940022

Paruch K, Petrůjová M. Furopyridines as inhibitors of protein kinases.

Patent: EP 3556756

Paruch, K.; Carbain, B.; Havel, S.; Všiansky, V.; Nikulenkov, F.; Krejčí, L. Substituted propanamides as inhibitors of nucleases.

Patent: CZ 305472

Paruch K, Petrůjová M. Substituted furo[3,2-b]pyridines intended for use as medicaments.

Patent: US 9902733

Paruch K, Petrůjová M, Němec V. Furopyridines as inhibitors of protein kinases.

Patent: JP 6386585

Paruch K, Petrůjová M, Němec V. Furopyridines as inhibitors of protein kinases.

Patent: US 9969741

Damborsky J, Nikulenkov F, Sisáková A, Havel Š, Krejčí L, Carbain B, Brezovsky J, Daniel L, Paruch K. Pyrazolotriazines as inhibitors of nucleases.

Patent: JP 6313906

Damborsky J, Nikulenkov F, Sisáková A, Havel Š, Krejčí L, Carbain B, Brezovsky J, Daniel L, Paruch K. Pyrazolotriazines as inhibitors of nucleases.

Patent: EP 2957562

Damborsky J, Nikulenkov F, Sisáková A, Havel Š, Krejčí L, Carbain B, Brezovsky J, Daniel L, Paruch K. Pyrazolotriazines as inhibitors of nucleases.